Virulence determinants, drug resistance and mobile genetic elements of Laribacter hongkongensis: a genome-wide analysis
نویسندگان
چکیده
منابع مشابه
Distribution and molecular characterization of tetracycline resistance in Laribacter hongkongensis.
OBJECTIVES Laribacter hongkongensis is a newly discovered bacterium associated with gastroenteritis and found in freshwater fish. Although isolates resistant to tetracycline have been described, their resistance mechanisms have not been studied. PATIENTS AND METHODS We describe the distribution and molecular characterization of tetracycline resistance in 48 L. hongkongensis isolates from huma...
متن کاملEcoepidemiology of Laribacter hongkongensis, a novel bacterium associated with gastroenteritis.
In a territory-wide surveillance study, Laribacter hongkongensis was isolated solely from freshwater fish (60% of grass carps, 53% of bighead carps, and 25% of mud carps). Comparing the pulsed-field gel electrophoresis patterns of fish and patient isolates revealed that most patient isolates were clustered together, suggesting that some clones could be more virulent.
متن کاملCharacterization of a novel cryptic plasmid, pHLHK26, in Laribacter hongkongensis.
We report the complete nucleotide sequence and characterization of a cryptic plasmid, pHLHK26, recovered from a strain of Laribacter hongkongensis isolated from a patient with community acquired gastroenteritis. pHLHK26 consists of 8700 bp, with G + C content 51.3%. The copy number (mean +/- SD) is 0.57 +/- 0.07 and it is stable after four passages (about 240 generations) in the absence of sele...
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Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. The genetic basis of the F. tularensis virulence is poorly understood. This study screened a total of 3,936 transposon mutants of the live vaccine strain for infection in a mouse model of respiratory tularemia by signature-tagged mutagenesis. We ...
متن کاملGenome-wide analysis of mobile genetic element insertion sites
Mobile genetic elements (MGEs) account for a significant fraction of eukaryotic genomes and are implicated in altered gene expression and disease. We present an efficient computational protocol for MGE insertion site analysis. ELAN, the suite of tools described here uses standard techniques to identify different MGEs and their distribution on the genome. One component, DNASCANNER analyses known...
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ژورنال
عنوان ژورنال: Cell & Bioscience
سال: 2011
ISSN: 2045-3701
DOI: 10.1186/2045-3701-1-17